cliffordfosterr
Guest
Apr 18, 2025
5:29 AM
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?Malegra FXT is a combination medication designed to address two common male sexual health issues: erectile dysfunction (ED) and premature ejaculation (PE). It contains two active ingredients: sildenafil citrate and fluoxetine.?
Sildenafil Citrate (100 mg): Malegra FXT is a phosphodiesterase type 5 (PDE5) inhibitor. During sexual arousal, nitric oxide is released in the penis, leading to the production of cyclic guanosine monophosphate (cGMP). cGMP causes the smooth muscles in the penile blood vessels to relax, allowing increased blood flow and resulting in an erection. PDE5 breaks down cGMP, but sildenafil inhibits this enzyme, thereby enhancing and prolonging the erection .?
Fluoxetine (40 mg): Fluoxetine is a selective serotonin reuptake inhibitor (SSRI). It works by blocking the reuptake of serotonin in the brain, increasing its levels in the synaptic cleft. Elevated serotonin levels help delay the ejaculatory reflex, thereby prolonging the time to ejaculation and improving control over ejaculation .?
Together, these components provide a dual-action approach: sildenafil addresses ED by enhancing blood flow to the penis, while fluoxetine manages PE by delaying ejaculation. This combination therapy offers a comprehensive solution for men experiencing both conditions simultaneously.?
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