kirazmattson
1130 posts
May 25, 2026
12:34 AM
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Malegra Professional lasts for hours because it contains sildenafil citrate, a PDE?5 inhibitor with a biological half?life of about 4 hours, so its effect on blood flow to the penis typically lasts roughly 4–6 hours after you take it. Why the effect lasts that long Sildenafil blocks the enzyme PDE?5 in penile blood vessels, which slows the breakdown of cGMP, the chemical that keeps blood vessels dilated and blood flow high enough for an erection—but only when you are sexually stimulated. Because the drug stays in your bloodstream at Malegra professional levels for a few hours, you can usually get spontaneous erections during that window, even if you take it 30–60 minutes before sex. Typical duration and limits For most men, the strongest effect is seen between about 30 minutes and 2.5 hours after the dose, then it gradually wears off over the next few hours. After about 4–6 hours, the response is usually much weaker, and by around 24 hours almost all of the drug is cleared from the body. Important safety note It does not cause a permanent erection; you still need sexual arousal, and the erection should go away after sex. If an erection lasts more than 4 hours (priapism), seek emergency care immediately, as this can damage penile tissue. If you tell me your age, blood?pressure status, and other medicines, I can help spell out whether this “hours?long” window is likely safe for you.
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